Amytis Towfighi, MD - Bibiliography

Peer Reviewed Original Research (first and senior authorship)

  1. Towfighi A, Skolasky RL, St Hillaire C, Conant K, McArthur JC. CSF soluble Fas correlates with the severity of HIV-associated dementia. Neurology. 2004 Feb 24;62(4):654-6. Review.

  2. Towfighi A, Saver JL, Engelhardt R, Ovbiagele B. A midlife stroke surge among women in the United States. Neurology. 2007 Nov 13;69(20):1898-904. Epub 2007 Jun 20.

  3. Towfighi A, Saver JL, Engelhardt R, Ovbiagele B. Factors associated with the steep increase in late midlife stroke occurrence among US men. J Stroke Cerebrovasc Dis. 2008 Jul-Aug;17(4):165-8.

  4. Towfighi A and Ovbiagele B. The impact of body mass index on mortality after stroke. Stroke. 2009 Aug;40(8):2704-8. Epub 2009 Jun 18.

  5. Towfighi A, Zheng L, Ovbiagele B. Sex-specific trends in midlife coronary heart disease risk and prevalence. Arch Intern Med. 2009 Oct 26;169(19):1762-6.

  6. Towfighi A, Ovbiagele B, Saver JL. Therapeutic milestone: stroke declines from the second to the third leading organ- and disease-specific cause of death in the United States. Stroke. 2010 Mar;41(3):499-503. Epub 2010 Jan 14.

  7. Towfighi A, Zheng L, Ovbiagele B. Weight of the obesity epidemic: rising stroke rates among middle-aged women in the United States. Stroke. 2010 Jul;41;1371-5. Epub 2010 May 27.

  8. Towfighi A, Markovic D, Ovbiagele B. Pronounced association of elevated serum homocysteine with stroke in subgroups of individuals: a nationwide study. J Neurol Sci. 2010 Nov 15;298(1-2):153-7.

  9. Towfighi A, Markovic D, Ovbiagele B. Persistent sex disparity in midlife stroke prevalence in the United States. Cerebrovasc Dis. 2011;31(4):322-8. Epub 2011 Jan 7.

  10. Towfighi A, Markovic D, Ovbiagele B. Temporal Trends in Age- and Sex-Specific Cardiac Risk after Stroke. International J Stroke. 2011. In press.

  11. Ovbiagele B, Markovic D, Towfighi A. Recent age- and gender-specific trends in mortality during stroke hospitalization in the United States. International J Stroke. 2011. In press.

  12. Towfighi A, Tai W, Markovic D, Ovbiagele B. Sex-Specific Temporal Trends in In-Hospital Mortality after Stroke among Middle-Aged Individuals in the United States. Stroke. 2011. In press.

  13. Towfighi A, Saver JL. Stroke Declines from Third to Fourth Leading Cause of Death in the United States: Historical Perspective and Challenges Ahead. Stroke. 2011. In press.

  14. Towfighi A, Markovic D, Ovbiagele B. Recent Patterns of Sex-Specific Midlife Stroke Hospitalization Rates in the United States. Stroke. 2011. In press.

  15. Towfighi A, Markovic D, Ovbiagele B. National Sex-Specific Trends in Myocardial Infarction Hospitalization Rates Among Middle-Aged Individuals. American Journal of Cardiology. 2011. In press.

Peer Reviewed Original Research (co-authorship)

  1. Ay H, Benner T, Arsava EM, Furie KL, Singhal AB, Jensen MB, Ayata C, Towfighi A, Smith EE, Chong JY, Koroshetz WJ, Sorensen AG. A computerized algorithm for etiologic classification of ischemic stroke: the Causative Classification of Stroke System. Stroke. 2007 Nov;38(11):2979-84. Epub 2007 Sep 27.

  2. Loh Y, Towfighi A, Liebeskind DS, MacArthur DL, Vespa P, Gonzalez NR, Tateshima S, Starkman S, Saver JL, Shi ZS, Jahan R, Viñuela F, Duckwiler GR. Basal ganglionic infarction before mechanical thrombectomy predicts poor outcome. Stroke. 2009 Oct;40(10):3315-20. Epub 2009 Aug 6.

  3. Loh Y, Towfighi A, Liebeskind DS, MacArthur DL, Vespa P, Gonzalez NR, Tateshima S, Starkman S, Saver JL, Shi ZS, Jahan R, Vinuela F, Duckwiler GR. Specific Multi-Modal MRI Patterns Prior to Mechanical Thrombectomy Predict Poor Outcome. Stroke. 2009;40:3315-3320.

  4. Biffi A, Halpin A, Towfighi A, Gilson A, Busl K, Rost N, Smith EE, Greenberg MS, Rosand J, Viswanathan A. Aspirin and recurrent intracerebral hemorrhage in cerebral amyloid angiopathy. Neurology. 2010 Aug 24;75(8):693-8.

  5. Cheng EM, Cunningham WE, Towfighi A, Sanossian N, Bryg RJ, Anderson TL, Guterman JJ, Gross-Schulman SG, Beanes S, Jones AS, Liu H, Ettner SL, Saver JL, Vickrey BG. Randomized, controlled trial of an intervention to enable stroke survivors throughout the Los Angeles county safety net to “stay with the guidelines". Circ Cardiovasc Qual Outcomes. 2011 Mar 1;4(2):229-34.

  6. Liebeskind DS, Sanossian N, Yong WH, Starkman S, Tsang MP, Moya AL, Zheng DD, Abolian AM, Kim D, Ali LK, Shah SH, Towfighi A, Ovbiagele B, Kidwell CS, Tateshima S, Jahan R, Duckwiler GR, Viñuela, F, Salamon N, Villablanca JP, Vinters HV, Marder VJ, Saver JL. CT and MRI Early Vessel Signs Reflect Clot Composition in Acute Stroke. Stroke. 2011 May;42(5):1237-43. Epub 2011 Mar 10.

  7. Loh Y, Liebeskind DS, Towfighi A, Vespa P, Starkman S, Saver JL, Gonzalez NR, Tateshima S, Jahan R, Shi ZS, Viñuela F, Duckwiler GR. Preprocedural Basal ganglionic infarction increases the risk of hemorrhagic transformation but not worse outcome following successful recanalization of acute middle cerebral artery occlusions. World Neurosurg. 2010 Dec;74(6):636-40.

  8. Lee M, Saver JL, Towfighi A, Chow J, Ovbiagele B. Efficacy of fibrates for cardiovascular risk reduction in persons with atherogenic dyslipidemia: A meta-analysis. Atherosclerosis. 2011 Apr 27.

Co-Investigator Studies

  1. Smith WS, Sung G, Saver J, Budzik R, Duckwiler G, Liebeskind DS, Lutsep HL, Rymer MM, Higashida RT, Starkman S, Gobin YP; Multi MERCI Investigators, Frei D, Grobelny T, Hellinger F, Huddle D, Kidwell C, Koroshetz W, Marks M, Nesbit G, Silverman IE. Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke. 2008 Apr;39(4):1205-12. Epub 2008 Feb 28.

  2. Pancioli AM, Broderick J, Brott T, Tomsick T, Khoury J, Bean J, del Zoppo G, Kleindorfer D, Woo D, Khatri P, Castaldo J, Frey J, Gebel J Jr, Kasner S, Kidwell C, Kwiatkowski T, Libman R, Mackenzie R, Scott P, Starkman S, Thurman RJ; CLEAR Trial Investigators. The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial. Stroke. 2008 Dec;39(12):3268-76. Epub 2008 Sep 4.

  3. Bang OY, Saver JL, Alger JR, Starkman S, Ovbiagele B, Liebeskind DS; UCLA Collateral Investigators. Determinants of the distribution and severity of hypoperfusion in patients with ischemic stroke. Neurology. 2008 Nov 25;71(22):1804-11.

  4. Shi ZS, Loh Y, Walker G, Duckwiler GR; MERCI and Multi-MERCI Investigators. Clinical outcomes in middle cerebral artery trunk occlusions versus secondary division occlusions after mechanical thrombectomy: pooled analysis of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI trials. Stroke. 2010 May;41(5):953-60. Epub 2010 Apr 8.

  5. Shi ZS, Loh Y, Walker G, Duckwiler GR; MERCI and Multi-MERCI Investigators. Endovascular thrombectomy for acute ischemic stroke in failed intravenous tissue plasminogen activator vesus non-intravenous tissue plasminogen activator patients: revascularization and outcomes stratified by the site of arterial occlusions. Stroke. 2010 Jun;41(6):1185-92. Epub 2010 Apr 29.

Peer Reviewed Original Research (submitted)

  1. Towfighi A, Markovic D, Ovbiagele B. Impact of Healthy Lifestyle Practices on Mortality after Stroke in the United States. 2011.

  2. Towfighi A, Markovic D, Ovbiagele B. Current National Patterns of Comorbid Diabetes Mellitus among Acute Ischemic Stroke Patients. 2011.

Reviews

  1. Towfighi A, Greenberg SM, Rosand J. Treatment and Prevention of Primary Intracerebral Hemorrhage. Seminars in Neurology. 2005;25(4):445-452.

  2. Towfighi A, Rosand J. Stop the Bleeding! An Update on the Prevention and Treatment of Intracerebral Hemorrhage. Stroke Clinical Updates, National Stroke Association. Vol XV. Issue 2. Mar-Apr 2005.

  3. Towfighi A, Ovbiagele B. Metabolic syndrome and stroke. Curr Diab Rep. 2008;8(1):37-41. Invited Review.

  4. Towfighi A, Ovbiagele B. Partial Peroxisome Proliferator-Activated Receptor Agonist Angiotensin Receptor Blockers: Potential Multipronged Strategy in Stroke Prevention. Cerebrovasc Dis 2008;26:106-112.

  5. Antillon D, Towfighi A. No Time to “Weight”: The Link Between Obesity and Stroke in Women. Women’s Health. 2011. In Press. Invited Review.

  6. Towfighi A, Boden-Albala B. Metabolic Syndrome and Lifestyle Interventions for the Secondary Prevention of Stroke. Continuum. 2011. In Press. Invited Review.

Book Chapters

  1. Towfighi A, Ali L, Heroux A, Saver JS. Cardiomyopathies and Other Myocardial Diseases. In: Interface of Neurology and Internal Medicine (Biller J, Ed). Lippincott Williams & Wilkins, 2007.

  2. Towfighi A, Liebeskind DS: Intracerebral Hemorrhage - Long-term Complications and Prevention. In: Stroke Essentials for Primary Care (Alway, D, Ed). Humana Press, 2008.

Peer Reviewed Platform Presentations at National/International Meetings

  1. Towfighi A, Skolasky R, St. Hillaire C, Conant K, McArthur JC. CSF Soluble Fas Correlates with the Course and Severity of HIV-associated Dementia. 9th Conference on Retroviruses and Opportunistic Infections, Seattle, WA. February 2002.

  2. Towfighi A, Saver JL, Liebeskind DS, Ovbiagele B. Inadequate Stroke Risk Factor Modification May Contribute to the Midlife Surge of Stroke in Women Compared to Men. International Stroke Conference, San Francisco, CA. February 2007.

  3. Towfighi A, Zheng L, Ellis W, Mack W, Vinters HV, Chui H, Zarow C. Hypertension is Associated with Hippocampal Sclerosis. International Stroke Conference, New Orleans, LA. February 2008.

  4. Towfighi A, Ovbiagele B. The Combination of Hypertension and Elevated Serum Homocysteine is Associated with Greater Stroke Occurrence. 7th International Conference on Homocysteine Metabolism. Prague, Czech Republic. June 24, 2009.

  5. Towfighi A, Ovbiagele B. Temporal Trends in Age- and Sex-specific Cardiac Risk After Stroke in the United States. International Stroke Conference, San Antonio, TX. February 24, 2010.

  6. Towfighi A, Gallup MA, Tai A, Guevara E, Ovbiagele B. Differences in Index Ischemic Stroke Characteristics in a Multiethnic Medically Underserved Population. International Stroke Conference, San Antonio, TX. February 25, 2010.

  7. Towfighi A, Ovbiagele B. Impact of Healthy Lifestyle Practices on Mortality after Stroke in the United States. American Academy of Neurology, Session S02: Cerebrovascular Disease: Stroke Epidemiology I. Toronto, Canada. April 13, 2010.

  8. Towfighi A, Markovic D, Ovbiagele B. Marked Upswing in Comorbid Diabetes Mellitus among Hospitalized Patients with Acute Ischemic Stroke in the United States. International Stroke Conference. Los Angeles CA. February 2011.

  9. Towfighi A, Markovic D, Ovbiagele B. Women Are Less Likely Than Men to Receive Reperfusion and Revascularization Therapies in the Setting of Acute Ischemic Stroke. Honolulu, HI. April 13, 2011

Poster Sessions (first and senior authorship)

  1. Towfighi A. Warfarin Use in Cerebral Amyloid Angiopathy. Poster, Massachusetts General Hospital Clinical Research Day, Cambridge, MA. May 2006.

  2. Towfighi A. Catastrophic Hemorrhage Due to Rapid Expansion of Remote Cerebral Microbleed During Thrombolysis for Acute Ischemic Stroke, American Society of Neuroimaging conference, Miami, FL. January 2007.

  3. Towfighi A. Arteritic Lenticulostriate Infarction Associated with Acute Posterior Multifocal Placoid Pigment Epitheliopathy. American Society of Neuroimaging conference, Miami, FL. January 2007.

  4. Towfighi A. Is It Safe to Anticoagulate Patients with Cerebral Amyloid Angiopathy? International Stroke Conference, San Francisco, CA. February 2007.

  5. Towfighi A. Does Overall Atherosclerotic Burden Contribute to Late Midlife Acceleration of Stroke in Men? Poster, International Stroke Conference, San Francisco, CA. February 2007.

  6. Towfighi A. The ‘Weight’ of the Obesity Epidemic: Rising Stroke Rates Among Middle-aged Women in the United States. International Stroke Conference, New Orleans, LA. February 2008.

  7. Towfighi A, Ovbiagele B, Saver J. A Milestone in Stroke Prevention and Treatment: Stroke Declines from Second to Third Leading Organ-Specific Cause of Death in the United States. International Stroke Conference, San Diego, CA. February 2009.

  8. Towfighi A, Zheng L, Ovbiagele B. Midlife Stroke Surge Accompanied by Rise in Coronary Heart Disease Risk Among Women in the United States. International Stroke Conference, San Diego, CA. February 2009.

  9. Chawla N, Yule A, Towfighi A. Large Vessel Atherothromboembolic Strokes are Associated with High Glycosylated Hemoglobin Levels. American Academy of Neurology. Seattle, WA. April 2009.

  10. Towfighi A, Tai A, Gallup MA, Guevara E, Ovbiagele B. Obesity is Independently and Strongly Linked to Symptomatic Cervicocephalic Atherosclerosis in a Medically Underserved Population. International Stroke Conference, San Antonio, TX. February 24, 2010.

  11. Towfighi A, Ovbiagele B. Persistent and Growing Sex Disparity in Midlife Stroke Prevalence Rates in the United States. International Stroke Conference, San Antonio, TX. February 25, 2010.

  12. Towfighi A, Ovbiagele B. Influence of Healthy Lifestyle Habits on Mortality After Stroke in the United States. Joint Conference - 50th Cardiovascular Disease Epidemiology and Prevention - and - Nutrition, Physical Activity and Metabolism Conference. San Francisco, CA. March 4, 2010.

  13. Towfighi A, Ovbiagele B. Pronounced Association of Elevated Serum Homocysteine with Stroke in Subgroups of Individuals: A Nationwide Study. American Academy of Neurology. Toronto, Canada. April 15, 2010.

  14. Towfighi A, Markovic D, Ovbiagele B. Recent Trends in Sex-Specific Stroke Incidence amongst 35-64 Year-Olds in the United States. Moderated Poster Presentation. International Stroke Conference. Los Angeles, CA. February 2011.

  15. Towfighi A, Tai W, Markovic D, Ovbiagele B. Sex-Specific Trends in Mortality amongst Hospitalized Stroke Patients in the United States International Stroke Conference. Los Angeles, CA. February 2011.

  16. Towfighi A, Valle N, Ovbiagele B. A Tale of Two Healthcare Systems: Disparities in Demographics and Clinical Characteristics between Two Ischemic Stroke Patient Populations Encountered in Los Angeles County. Honolulu, HI. April 12, 2011.

Cited Works

  1. Stroke Symptoms May Differ in Women. WebMD. February 2007.

  2. Stroke Prevalence in Middle-Aged Women Higher Than Men. Medscape Medical News. February 2007.

  3. Middle-Aged Women Gaining Weight, Raising Their Stroke Risk. The Washington Post. February 2008.

  4. Women's Spare Tire Tied to More Strokes. WebMD. February 2008.

  5. A Surge In Strokes. Newsweek. March 2008.

  6. Patterns: For Heart Attacks, Shifts In Gender Gap. The New York Times. October 2009.

  7. Rates of Heart Attacks Increasing for Middle-Aged Women, Study Shows. Los Angeles Times. October 2009.

  8. Heart Disease Gender Gap Narrows. U.S.News & World Report. October 2009.

  9. Belly Fat Is Culprit in Stroke Gender Gap. WebMD. February 2010.



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